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Precision Antibody Therapy ART5803 Blocks NMDA Receptor Damage in Anti-NMDA Encephalitis Models
Researchers at Arialys Therapeutics published preclinical data in Nature Communications showing that ART5803, a humanized monovalent antibod...
Read More — Precision Antibody Therapy ART5803 Blocks NMDA Receptor Damage in Anti-NMDA Encephalitis Models »When ADEM Looks Like Migraine: A Case Study in Delayed Diagnosis
A 35-year-old man's ADEM was initially misdiagnosed as complex migraine, leading to dangerous delays in treatment. This case report from Heb...
Read More — When ADEM Looks Like Migraine: A Case Study in Delayed Diagnosis »How Knowing About APS-3B Led Doctors to Two Hidden Diagnoses in a Patient with Hashimoto's
A 2025 case report from Japan shows how applying the APS-3B framework to a patient with Hashimoto's disease led to the correct diagnosis of...
Read More — How Knowing About APS-3B Led Doctors to Two Hidden Diagnoses in a Patient with Hashimoto's »The Youngest APS-2 Patient on Record: A Toddler's Case Illuminates How Early Autoimmunity Can Cluster
A case report from China describes a 3-year-old girl diagnosed with APS-2, making her the youngest patient with this condition ever document...
Read More — The Youngest APS-2 Patient on Record: A Toddler's Case Illuminates How Early Autoimmunity Can Cluster »FDA Grants Fast Track Designation to Bempikibart for Alopecia Areata, Spotlighting New Immune Target
The FDA granted Fast Track designation to bempikibart, a novel anti-IL-7Rα antibody from Q32 Bio, for the treatment of alopecia areata, acc...
Read More — FDA Grants Fast Track Designation to Bempikibart for Alopecia Areata, Spotlighting New Immune Target »Immunotherapy for Autoimmune Encephalitis: What Patients and Families Should Know
A comprehensive April 2025 review in Cell Death Discovery outlines how immunotherapy has transformed outcomes in autoimmune encephalitis and...
Read More — Immunotherapy for Autoimmune Encephalitis: What Patients and Families Should Know »FDA Grants Fast Track Status to New CAR-T Therapy for Lupus, Myositis, and Scleroderma
The FDA granted Fast Track designation to a new CAR-T therapy targeting multiple autoimmune diseases, signaling potential for faster develop...
Read More — FDA Grants Fast Track Status to New CAR-T Therapy for Lupus, Myositis, and Scleroderma »A New Complement Inhibitor Shows Promise for Hard-to-Treat Autoimmune Hemolytic Anemia
A March 2025 case report describes how iptacopan, a new complement pathway inhibitor, achieved rapid improvement in a patient with severe wa...
Read More — A New Complement Inhibitor Shows Promise for Hard-to-Treat Autoimmune Hemolytic Anemia »Scientists Discover Immune “Checkpoint” System That Prevents Autoimmune Disease
“They discovered important mechanisms that prevent B cells from attacking the body’s own tissues.”
Read More — Scientists Discover Immune “Checkpoint” System That Prevents Autoimmune Disease »A Severe Guillain-Barré Variant Shows Promising Response to Efgartigimod in New Case Report
A case report from China describes significant improvement in a patient with acute motor axonal neuropathy (AMAN) who did not respond to sta...
Read More — A Severe Guillain-Barré Variant Shows Promising Response to Efgartigimod in New Case Report »NIH Researchers Find an Existing Drug Can Treat a Rare Multi-Organ Autoimmune Disorder
NIH researchers report that ruxolitinib, a JAK inhibitor already approved for other blood conditions, can drive clinical remission in patien...
Read More — NIH Researchers Find an Existing Drug Can Treat a Rare Multi-Organ Autoimmune Disorder »Improved Hormone Delivery Methods Studied for Addison’s Disease
Researchers are exploring ways to better mimic natural hormone rhythms in Addison’s disease.
Read More — Improved Hormone Delivery Methods Studied for Addison’s Disease »