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General Autoimmune News

Professor Ranjeny Thomas. Credit: University of Queensland

World-first immunotherapy trial to treat type 1 diabetes

Researchers at the University of Queensland have initiated a groundbreaking clinical trial to evaluate ASITI-201, an investigational immunotherapy designed to treat type 1 diabetes (T1D). Developed under the leadership of Professor Ranjeny Thomas, ASITI-201 combines a pancreatic protein with vitamin D to modulate the immune system, aiming to protect insulin-producing

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FDA Grants Fast Track Status to Allogene's autoimmune therapy

FDA grants fast track status to Allogene’s autoimmune therapy

Allogene Therapeutics, a biotech company, has received “Fast Track” status from the U.S. Food and Drug Administration (FDA) for its new therapy, ALLO-329, aimed at treating autoimmune diseases like systemic lupus erythematosus (SLE), immune-mediated inflammatory diseases (IIM), and systemic sclerosis (SSc). This designation is granted to expedite the development and

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Articles

News

Timely Diagnosis Key To Treating Childhood Rheumatic Disorders: AIIMS Experts

This article from Outlook India highlights insights shared by leading pediatric rheumatology experts at AIIMS (All India Institute of Medical Sciences), emphasizing the crucial role of early diagnosis in the effective management and treatment of childhood rheumatic disorders. These disorders, which include conditions like juvenile idiopathic arthritis (JIA), lupus, vasculitis,

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New guidelines for monitoring IBD patients to prevent bowel cancer

This article from Medical Xpress reports on the release of new clinical guidelines designed to help reduce the risk of bowel cancer in patients with inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis. Published by an international panel of gastroenterologists and cancer prevention specialists, the guidelines offer

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World-first immunotherapy trial to treat type 1 diabetes

Researchers at the University of Queensland have launched the world’s first clinical trial of an innovative immunotherapy designed to treat type 1 diabetes (T1D), a chronic autoimmune condition in which the immune system attacks insulin-producing beta cells in the pancreas. The investigational therapy, known as ASITI-201, aims to retrain the

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Gastrointestinal Motility Abnormalities Prevalent in Patients With Diabetes

This article from Endocrinology Advisor highlights recent research showing that gastrointestinal (GI) motility abnormalities are a frequent and often underrecognized complication in individuals with diabetes mellitus, particularly type 1 and type 2 diabetes. GI motility disorders refer to problems with the movement of food through the digestive tract, and in

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Research Studies

Blood nerve barrier permeability enables nerve targeting of circulating nanoparticles in experimental autoimmune neuritis

This peer-reviewed study published in Nature Scientific Reports investigates the relationship between gut microbiota composition and autoimmune thyroid diseases (AITDs), particularly Hashimoto’s thyroiditis and Graves’ disease. The research offers compelling evidence that individuals with AITDs have distinct alterations in their gut microbial communities compared to healthy individuals, supporting growing interest

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Serum metabolomic analysis in patients with Hashimoto’s thyroiditis positive for TgAb or TPOAb: a preliminary study

This peer-reviewed study, published in Nature Scientific Reports, explores how specific patterns in the gut microbiome can be used to distinguish Hashimoto’s thyroiditis from other autoimmune diseases. The research offers compelling evidence that the composition and diversity of gut bacteria in patients with Hashimoto’s present a unique microbial signature—suggesting a

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Autoimmune Archive
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